Scintigraphy in hypothyroid neonates.

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Scintigraphy in hypothyroid neonates.

Sir, I read with interest the article by Tindall, Griffiths & Penn.' They conclude that 'scintigraphy has been shown to be of little practical value in... patients with hypothyroidism and therefore should not be requested'. This does not hold true for neonates who are identified by newborn screening to have connatal hypothyroidism, i.e. thyrotrophin above 7 mU/l and T4 below 6 ug/dl, as defined...

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Free triiodothyronine measured in dried blood spots from normal, low-birth-weight, and hypothyroid neonates.

Free triiodothyronine (FT3) has rarely been studied in neonates, primarily because of obvious problems in obtaining serum samples from neonates for research purposes. We adapted an analog radioimmunoassay for measuring FT3 in dried blood samples and used it to assay 361 samples selected from those collected for the screening for neonatal hypothyroidism. The mean FT3 concentration in healthy neo...

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Free thyroxin measured in dried blood spots from normal, low-birth-weight, and hypothyroid neonates.

We have adapted a new radioimmunoassay for free thyroxin (FT4) measurement in dried blood spots for use in neonatal screening for hypothyroidism. The method is easy, fast, and cheap. Within-assay and between-assay CVs are respectively 9.6% and 13.2%. In 997 neonates three days postpartum with normal thyrotropin concentrations, the mean FT4 concentration was 27.2 pmol/L (SD 7.3 pmol/L). There wa...

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Urine and milk iodine concentrations in healthy and congenitally hypothyroid neonates and their mothers.

INTRODUCTION In view of the high prevalence of Congenital Hypothyroidism (CH) in Iran, in this study we evaluated the role of iodine in the aetiology of CH by comparing urine and milk iodine concentrations in healthy and congenitally hypothyroid neonates and their mothers. MATERIAL AND METHODS In a cross-sectional study, urinary iodine concentrations (UIC) in newborns with CH, as well as UIC ...

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Alteration in postnatal development of masseter innervation in hypothyroid rats

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1988

ISSN: 0032-5473

DOI: 10.1136/pgmj.64.751.413